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1

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile

Hunt, Hazel J., Belanoff, Joseph K., Golding, Emily, Gourdet, Benoit, Phillips, Timothy, Swift, Denise, Thomas, Jennifer, Unitt, John F., Walters, Iain

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 933 KB

english, 2015

2

Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide

Benoit Gourdet, Dr. Hon Wai Lam

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

3

Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide

Benoit Gourdet, Dr. Hon Wai Lam

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 376 KB

english, 2010

4

ChemInform Abstract: Stereoselective Synthesis of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation of Ynamides.

Benoit Gourdet, Hon Wai Lam

Journal:

Year:

2009

File:

PDF, 43 KB

2009

5

ChemInform Abstract: Preparation of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation and Hydrozincation of Ynamides.

Benoit Gourdet, Mairi E. Rudkin, Ciorsdaidh A. Watts, Hon Wai Lam

Journal:

Year:

2010

File:

PDF, 70 KB

2010

6

ChemInform Abstract: Rhodium-Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents.

Benoit Gourdet, Mairi E. Rudkin, Hon Wei Lam

Journal:

Year:

2010

File:

PDF, 42 KB

2010

7

ChemInform Abstract: Rhodium-Catalyzed Carbometalation of Ynamides with Organoboron Reagents.

Benoit Gourdet, Donna L. Smith, Hon Wai Lam

Journal:

Year:

2011

File:

PDF, 33 KB

2011

8

ChemInform Abstract: Di(1H,1H,2H,2H-perfluorooctyl)-dibenzo-18-crown-6: A “Light Fluorous” Recyclable Phase Transfer Catalyst.

Benoit Gourdet, Kuldip Singh, Alison M. Stuart, Jose A. Vidal

Journal:

Year:

2011

File:

PDF, 25 KB

2011

9

ChemInform Abstract: Catalytic Asymmetric Dihydroxylation of Enamides and Application to the Total Synthesis of (+)-Tanikolide.

Benoit Gourdet, Hon Wai Lam

Journal:

Year:

2011

File:

PDF, 35 KB

2011

10

Di(1H,1H,2H,2H-perfluorooctyl)-dibenzo-18-crown-6: A “light fluorous” recyclable phase transfer catalyst

Benoit Gourdet, Kuldip Singh, Alison M. Stuart, José A. Vidal

Journal:

Journal of Fluorine Chemistry

Year:

2010

Language:

english

File:

PDF, 593 KB

english, 2010

11

Extremely regio-regular poly (3-alkylthiophene)s from simplified chain-growth Grignard metathesis polymerisations and the modification of their chain-ends

Roger C Hiorns, Abdel Khoukh, Benoit Gourdet, Christine Dagron-Lartigau

Journal:

Polymer International

Year:

2006

Language:

english

File:

PDF, 328 KB

english, 2006

12

Rhodium-catalyzed carbometalation of ynamides with organoboron reagents

Benoit Gourdet, Donna L. Smith, Hon Wai Lam

Journal:

Year:

2010

Language:

english

File:

PDF, 607 KB

english, 2010

13

Stereoselective Synthesis of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation of Ynamides

Gourdet, Benoit, Lam, Hon Wai

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

14

Rhodium-Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents

Gourdet, Benoit, Rudkin, Mairi E., Lam, Hon Wai

Journal:

Organic Letters

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

15

Preparation of Multisubstituted Enamides via Rhodium-Catalyzed Carbozincation and Hydrozincation of Ynamides

Gourdet, Benoit, Rudkin, Mairi E., Watts, Ciorsdaidh A., Lam, Hon Wai

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.67 MB

english, 2009

16

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Amsterdam, , Netherlands (Sunday 1 July 2012)] Adaptive Optics Systems III - TMT DMs final design and advanced prototyping results at Cilas

Sinquin, Jean-Christophe, Bastard, Arnaud, Boyer, Corinne, Cornette, Sébastien, Cousty, Raphaël, Ellerbroek, Brent, Gilbert, Xavier, Gourdet, Benoit, Grasser, Régis, Groeninck, Denis, Guillemard, Clau

Year:

2012

Language:

english

File:

PDF, 2.00 MB

english, 2012

17

Identification of the Clinical Candidate ( R )-(1-(4-Fluorophenyl)-6-((1-methyl-1 H -pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1 H -pyrazolo[3,4- g ]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist

Hunt, Hazel J., Belanoff, Joseph K., Walters, Iain, Gourdet, Benoit, Thomas, Jennifer, Barton, Naomi, Unitt, John, Phillips, Timothy, Swift, Denise, Eaton, Emily

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017